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KMID : 0380620080400050580
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Korean Journal of Food Science and Technology
2008 Volume.40 No. 5 p.580 ~ p.585
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Effects of Defatted Soybean Grits on Lipid Metabolism in Rats Fed with High-fat Diet
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Kim Hyun-Jeong
Ji Young-Ju
Lee Sung-Gyu
Choi Jun-Hyeok
Jeong Hyun-Jin
Lee Eun-Ju
Lee Sam-Bin
Lee In-Seon
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Abstract
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The principal objective of this study was to determine the effects of defatted soybean grits (DSG) on body lipid metabolism with 4 weeks of feeding on a high-fat diet. The rats were divided into the following 4 groups: control group (Con), control group treated with 20% DSG (C20D), high-fat group (HF), and high-fat group treated with 20% DSG (HF20D). The plasma total cholesterol and LDL-cholesterol concentrations were significantly lower in the HF20D group than in the HF group. On the other hand, the DSG supplement resulted in a significant increase in plasma HDL-cholesterol levels. The DSG supplement reduced the hepatic total lipid, total cholesterol, and triglyceride contents as compared to what was observed in the HF diet groups. In addition, the fecal total cholesterol and triglyceride contents increased in the DSG treatment groups. The hepatic HMG-CoA reductase activities were demonstrated to be significantly lower in the HF20D group than in the HF group. These results showed that the DSG powder lowered plasma cholesterol levels, tissue lipid contents, and cholesterol accumulation in the rats.
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KEYWORD
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defatted soybean grits, high-fat diet, cholesterol, lipid profiles
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